Plasticity of glutamate synaptic mechanisms
نویسندگان
چکیده
منابع مشابه
Molecular mechanisms of synaptic plasticity
Molecular mechanisms of synaptic plasticity Implications for immediate early gene expression and learning
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Long-term potentiation (LTP) and long-term depression (LTD) are important forms of synaptic plasticity thought to underlie many brain processes such as those involved in brain development, memory, and drug addiction. The metabotropic glutamate receptors (mGluRs) are capable of inducing both LTP and LTD, and also of modulating the induction of plasticity initiated by other receptor systems. Alth...
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Brain is a sophisticated information processing and storage system with capabilities unmatched by any manmade computers. Neurons, the primary building blocks of the brain are structurally and functionally specialized to do these functions. The neuronal membrane is equipped with several types of ion channel and ion pump proteins which enable it to conduct nerve impulses in the form of electroche...
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Homeostatic synaptic plasticity is a negative feedback mechanism that neurons use to offset excessive excitation or inhibition by adjusting their synaptic strengths. Recent findings reveal a complex web of signaling processes involved in this compensatory form of synaptic strength regulation, and in contrast to the popular view of homeostatic plasticity as a slow, global phenomenon, neurons may...
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TBS (Theta Burst Stimulation) and PBs (Primed Bursts) are among effective tetanic stimulations for induction of LTP in hippocampus. Recent studies have indicated that TBS is effective in LTP induction in layer III synapses of neocortex, only if applied to layer IV. However, the possibility of neocortical LTP induction using PBs, has not yet been investigated. Sensory deprivation greatly influ...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2010
ISSN: 0013-9580
DOI: 10.1111/j.1528-1167.2010.02803.x